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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZZZ3
All Species:
22.73
Human Site:
Y488
Identified Species:
83.33
UniProt:
Q8IYH5
Number Species:
6
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYH5
NP_056349.1
903
102023
Y488
E
D
D
D
P
D
V
Y
Y
F
E
S
D
H
V
Chimpanzee
Pan troglodytes
XP_513508
903
101976
Y488
E
D
D
D
P
D
V
Y
Y
F
E
S
D
H
V
Rhesus Macaque
Macaca mulatta
XP_001103569
903
101870
Y488
E
D
D
D
P
D
V
Y
Y
F
E
S
D
H
V
Dog
Lupus familis
XP_547324
903
102069
Y488
E
D
D
D
P
D
V
Y
Y
F
E
S
D
H
V
Cat
Felis silvestris
Mouse
Mus musculus
Q6KAQ7
910
102288
Y495
E
D
D
D
P
D
V
Y
Y
F
E
S
D
H
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506419
1003
111451
Y588
E
D
D
D
P
D
V
Y
Y
F
E
S
D
H
V
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_391891
388
44955
E15
C
Q
D
E
E
P
N
E
F
Y
F
E
S
D
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.5
95.6
N.A.
86.6
N.A.
N.A.
70.7
N.A.
N.A.
N.A.
N.A.
N.A.
22.5
N.A.
N.A.
Protein Similarity:
100
99.8
99.3
98.2
N.A.
92.4
N.A.
N.A.
78.3
N.A.
N.A.
N.A.
N.A.
N.A.
30.7
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
86
100
86
0
86
0
0
0
0
0
0
86
15
0
% D
% Glu:
86
0
0
15
15
0
0
15
0
0
86
15
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
15
86
15
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
86
15
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
86
15
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
86
15
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
86
0
0
0
0
0
0
0
86
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
86
86
15
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _